Dear all, The next seminar in our series of statistics talks for people interested in quantitative methods in biology and medicine will take place Thursday 18 October at 11h00 in the Génopode Building in Dorigny (room 2020). The speakers will be Darlene Goldstein and Alix Leboucq from the EPFL, who will talk about "Combining microarray studies with missing information". Abstract: Meta-analysis of microarray studies to produce an overall gene list is relatively straightforward when complete data are available. When some studies are missing information (for example, some studies have only a ranked list of genes instead of complete primary data), a common approach is to reduce all studies to ranked lists prior to combining. Since this step entails a loss of information, we wondered whether we could improve the final list by attempting to preserve the information available for each study. We therefore consider a modeling approach to combine the studies using the type of information available in each study: full data matrix, summary statistics, or ranks for each gene. We will discuss progress in the development of the model, some results from a simulation study of model performance and from real data. You can find more information about the forum on our web page at http://moodle.unil.ch/course/view.php?id=2729 Hope to see you there ! Frédéric (for the organizers: Jérôme Goudet, Valentin Rousson, Frédéric Schütz)