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<p class="MsoNormal"><span style="font-size:11.0pt;color:black;mso-fareast-language:EN-US">Dear All,</span><span style="font-size:11.0pt;mso-fareast-language:EN-US"><o:p></o:p></span></p>
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<span style="font-size:11.0pt;color:black;mso-fareast-language:EN-US"> </span><span style="font-size:11.0pt;mso-fareast-language:EN-US"><o:p></o:p></span></p>
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<span style="font-size:11.0pt;color:black;mso-fareast-language:EN-US">We </span><span lang="EN-US" style="font-size:11.0pt;mso-fareast-language:EN-US">would like to
</span><span style="font-size:11.0pt;color:black;mso-fareast-language:EN-US">announce th</span><span lang="EN-US" style="font-size:11.0pt;color:black;mso-fareast-language:EN-US">at</span><span lang="EN-US" style="font-size:11.0pt;mso-fareast-language:EN-US">
t</span><span style="font-size:11.0pt;color:black">here are a few seats left for the SIB course</span><span lang="EN-US" style="font-size:11.0pt;color:black">:</span><span lang="EN-US" style="font-size:11.0pt"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;mso-fareast-language:EN-US"><o:p> </o:p></span></p>
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<b><span style="font-size:11.0pt;color:red;mso-fareast-language:EN-US"><a href="https://www.sib.swiss/training/course/20220915_NGSGV"><span style="color:red">NGS - Genome variant analysis</span></a></span></b><span style="font-size:11.0pt;mso-fareast-language:EN-US"><o:p></o:p></span></p>
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<span style="font-size:11.0pt;color:black"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;color:black">we were forced to change the dates to <b>26-27 September</b></span><b><span lang="EN-US" style="font-size:11.0pt;color:black"> 2022</span></b><span style="font-size:11.0pt;color:black">. It will
still be held in Bern and only in person.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;color:black"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;color:black;mso-fareast-language:EN-US">The detection of genetic variation is of major interest in various disciplines spanning from ecology and evolution research to inherited disease discovery and precision
oncology. Next generation sequencing (NGS) methods are very powerful for the detection of genomic variants. Thanks to its throughput and cost-efficiency it enables the detection of a large number of variants in a large number of samples.<span class="apple-converted-space"> </span></span><span style="font-size:11.0pt;mso-fareast-language:EN-US"><o:p></o:p></span></p>
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<span style="font-size:11.0pt;color:black;mso-fareast-language:EN-US">In this two-day course</span><span lang="EN-US" style="font-size:11.0pt;color:black;mso-fareast-language:EN-US">,</span><span class="apple-converted-space"><span style="font-size:11.0pt;color:black;mso-fareast-language:EN-US"> </span></span><span style="font-size:11.0pt;color:black;mso-fareast-language:EN-US">we
will cover the steps from read alignment to variant calling and annotation. We will mainly focus on the detection of germline mutations by following the GATK best practices.<span class="apple-converted-space"> </span>This<span class="apple-converted-space"> </span></span><span lang="EN-US" style="font-size:11.0pt;color:black;mso-fareast-language:EN-US">course</span><span class="apple-converted-space"><span style="font-size:11.0pt;color:black;mso-fareast-language:EN-US"> </span></span><span style="font-size:11.0pt;color:black;mso-fareast-language:EN-US">is
intended for life scientists who are already familiar with general concepts of NGS technologies and want to expand their knowledge and skills on variant analysis.</span><span style="font-size:11.0pt;mso-fareast-language:EN-US"><o:p></o:p></span></p>
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<span style="font-size:11.0pt;color:black;mso-fareast-language:EN-US"> </span><span style="font-size:11.0pt;mso-fareast-language:EN-US"><o:p></o:p></span></p>
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<span style="font-size:11.0pt;color:black;mso-fareast-language:EN-US">Further detailed information, prerequisites and application form are available<span class="apple-converted-space"> </span><a href="https://www.sib.swiss/training/course/20220915_NGSGV">here</a>.</span><span style="font-size:11.0pt;mso-fareast-language:EN-US"><o:p></o:p></span></p>
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<span style="font-size:11.0pt;color:black;mso-fareast-language:EN-US"> </span><span style="font-size:11.0pt;mso-fareast-language:EN-US"><o:p></o:p></span></p>
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<span style="font-size:11.0pt;color:black;mso-fareast-language:EN-US">Should you have any questions, please don't hesitate to contact us at
<a href="mailto:training@sib.swiss">training<span lang="EN-US">@sib.swiss</span></a></span><span lang="EN-US" style="font-size:11.0pt;color:black;mso-fareast-language:EN-US">.</span><span style="font-size:11.0pt;mso-fareast-language:EN-US"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:11.0pt;color:black;mso-fareast-language:EN-US"> </span><span style="font-size:11.0pt;mso-fareast-language:EN-US"><o:p></o:p></span></p>
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<span lang="FR" style="font-size:11.0pt;color:black;mso-fareast-language:EN-US">Best wishes</span><span style="font-size:11.0pt;color:black;mso-fareast-language:EN-US">,</span><span style="font-size:11.0pt;mso-fareast-language:EN-US"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;mso-fareast-language:EN-US"> <o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:11.0pt;mso-fareast-language:EN-US">Valeria</span><span style="font-size:11.0pt;mso-fareast-language:EN-US"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;mso-fareast-language:EN-US"> <o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:11.0pt;color:#201F1E;border:none windowtext 1.0pt;padding:0cm;background:white;mso-fareast-language:EN-US">--</span><span style="font-size:11.0pt;mso-fareast-language:EN-US"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:11.0pt;color:#201F1E;mso-fareast-language:EN-US"><img border="0" width="160" height="88" style="width:1.6666in;height:.9166in" id="Picture_x0020_1" src="cid:image002.png@01D8AB20.6BBC5F00" alt="signature_3481920690"></span><span style="font-size:11.0pt;mso-fareast-language:EN-US"><o:p></o:p></span></p>
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<p class="MsoNormal"><b><span style="font-size:11.0pt;font-family:Helvetica;color:#201F1E;border:none windowtext 1.0pt;padding:0cm;background:white;mso-fareast-language:EN-US">Valeria Di Cola, PhD</span></b><span style="font-size:11.0pt;font-family:Helvetica;color:#201F1E;mso-fareast-language:EN-US"><br>
<span style="border:none windowtext 1.0pt;padding:0cm;background:white">SIB Training</span><br>
</span><b><span style="font-size:11.0pt;font-family:Helvetica;color:#C82613;border:none windowtext 1.0pt;padding:0cm;background:white;mso-fareast-language:EN-US">SIB
</span></b><b><span style="font-size:11.0pt;font-family:Helvetica;color:#201F1E;border:none windowtext 1.0pt;padding:0cm;background:white;mso-fareast-language:EN-US">| Swiss Institute of Bioinformatics</span></b><span style="font-size:11.0pt;font-family:Helvetica;color:#201F1E;mso-fareast-language:EN-US"><br>
<span style="border:none windowtext 1.0pt;padding:0cm;background:white">Quartier Sorge, Bâtiment Amphipôle</span></span><span style="font-size:11.0pt;mso-fareast-language:EN-US"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:Helvetica;color:#201F1E;border:none windowtext 1.0pt;padding:0cm;background:white;mso-fareast-language:EN-US">1015 Lausanne - Switzerland</span><span style="font-size:11.0pt;font-family:Helvetica;color:#201F1E;mso-fareast-language:EN-US"><br>
<span style="border:none windowtext 1.0pt;padding:0cm;background:white">valeria.dicola@sib.swiss - </span></span><span style="font-size:11.0pt;mso-fareast-language:EN-US"><a href="http://www.sib.swiss/" target="_blank"><span style="font-family:Helvetica;border:none windowtext 1.0pt;padding:0cm;background:white">www.sib.swiss</span></a><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:Helvetica;color:#201F1E;mso-fareast-language:EN-US"> </span><span style="font-size:11.0pt;mso-fareast-language:EN-US"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:11.0pt;mso-fareast-language:EN-US"> <o:p></o:p></span></p>
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